DOTAP
- Product Name
- DOTAP
- CAS No.
- 144189-73-1
- Chemical Name
- DOTAP
- Synonyms
- DOTAP;DOTAP MS;DOTAP METHOSULFATE;DOTAP methyl sulfate;TRANSFECTION REAGENT;18:1 TAP (DOTAP, MS Salt);DOTAP Transfection Reagent;TRANSFAST(TM) TRANSFECTION REAGENT;TFX(TM) REAGENTS TRANSFECTION TRIO;DOTAP Liposomal Transfection Reagent
- CBNumber
- CB3122792
- Molecular Formula
- C42H80NO4.CH3O4S
- Formula Weight
- 774.19
- MOL File
- 144189-73-1.mol
DOTAP Property
- Density
- 1.11 g/cm3
- storage temp.
- 2-8°C
- form
- buffered aqueous suspension
- color
- clear to hazy colorless to faint yellow
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H336May cause drowsiness or dizziness
H351Suspected of causing cancer
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 11202375001
- Product name
- DOTAP Liposomal Transfection Reagent
- Purity
- N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl-sulfate
- Packaging
- 5x400μL
- Price
- $598
- Updated
- 2024/03/01
- Product number
- T8198-02
- Product name
- Transfection Reagent
- Packaging
- 120ul
- Price
- $1042
- Updated
- 2021/12/16
- Product number
- FD157467
- Product name
- N-[1-(2,3-Dioleoyloxy)propyl]-n,n,n-trimethylammonium methyl-sulfate
- Packaging
- 250mg
- Price
- $325
- Updated
- 2021/12/16
- Product number
- FD157467
- Product name
- N-[1-(2,3-Dioleoyloxy)propyl]-n,n,n-trimethylammonium methyl-sulfate
- Packaging
- 500mg
- Price
- $500
- Updated
- 2021/12/16
- Product number
- CBL0000340
- Product name
- DOTAP METHOSULFATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $605.15
- Updated
- 2021/12/16
DOTAP Chemical Properties,Usage,Production
Description
18:1 TAP (DOTAP, MS Salt) is a cationic derivative of trimethylammonium linked with two 18-carbon fatty acid tails with single alkene groups in each tail. 18:1 TAP is a cationic liposome-forming compound that may be used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells.
Uses
The DOTAP (N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl-sulfate) Liposomal Transfection Reagent is a liposome formulation of the cationic lipid DOTAP. DOTAP can be used for the highly efficient transfection of DNA including yeast artificial chromosomes (YACs) into eukaryotic cells for transient or stable gene expression, and is also suitable for the efficient transfer of other negatively charged molecules, such as RNA, oligonucleotides, nucleotides, ribonucleo-protein (RNP) complexes, and proteins into research samples of mammalian cells.
General Description
DOTAP Liposomal Transfection Reagent is a liposome formulation of the cationic lipid DOTAP. Unlike other liposomal reagents, it produces highly efficient transfections both in the presence and absence of serum. It can also be successfully used for in vivo applications. Mixing DOTAP with DNA results in spontaneously formed stable complexes. These complexes can be added directly to the cell culture medium. This method of DNA transfer is very gentle, avoiding the cytotoxic effects commonly encountered with lipofection or other transfection methods.
Biochem/physiol Actions
DOTAP (1,2-dioleoyl-3-trimethylammonium-propane) is a cationic lipid, used for in vitro and in vivo nucleic acid and protein delivery. The lipid composition and cell type affects the transfection potential of DOTAP. DOTAP mediates gene knockdown technique in hematopoietic stem cells (HSCs).
DOTAP Preparation Products And Raw materials
Raw materials
Preparation Products
DOTAP Suppliers
View Lastest Price from DOTAP manufacturers
- Product
- DOTAP 144189-73-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- DOTAP 144189-73-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-08
- Product
- 1,2-dioleoyl-3-trimethylammonium propane (methyl sulfate salt) 144189-73-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1
- Release date
- 2021-07-07